Laparoscopic appendectomy in a child with hemophilia A with inhibitors receiving prophylactic treatment with emicizumab
نویسندگان
چکیده
Surgeries in patients treated prophylactically with emicizumab (including surgical procedures a high risk of postoperative bleeding) are not associated higher risks or technical difficulties compared operations receiving standard replacement therapy. On the contrary, presence blood and its maintenance permanent basic hemostasis allow for reduction doses infusion time bypassing agents. Patients undergoing bleeding require an additional hemostatic treatment during first two three days after surgery. Then duration should be determined individually. We recommend use recombinant activated factor VII prevention/control hemophilia A inhibitors who currently have received it past 6 months. If anti-inhibitor coagulant complex is required, daily dose exceed 100 units/kg. Here we report case laparoscopic appendectomy 8-year-old child prophylactic emicizumab. The patient's parents gave their consent to child's data, including photographs, research purposes publications.
منابع مشابه
Rituximab for Treatment of Hemophilia A with High-Responder Inhibitors
Background: The development of inhibitors is a complication factor replacement therapy in hereditary factor VIII deficiency. Several management options are available for the treatment of inhibitor. Rituximab, a monoclonal antibody against CD20, reduces inhibitor level in rare bleeding disorders. The aim of this study was to evaluate the effectiveness of rituximab in lowering or eliminating the ...
متن کاملTwo-incision laparoscopic appendectomy for a severe hemophilia A child patient with coagulation factor VII deficiency
RATIONALE The main complication of patients with severe hemophilia is recurrent bleeding events that usually affected musculoskeletal contractures. And replacement therapy methods were continuously improved to minimize adverse impacts brought by those complications. However, only several cases reported about the appendectomy for hemophilia A. We report a case of acute appendicitis treated by tw...
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ژورنال
عنوان ژورنال: Voprosy gematologii/onkologii i immunopatologii v pediatrii
سال: 2022
ISSN: ['1726-1708', '2414-9314']
DOI: https://doi.org/10.24287/1726-1708-2022-21-3-115-118